Principles of mRNA control by human PUM proteins elucidated from multimodal experiments and integrative data analysis

Wolfe, MB; Schagat, TL; Paulsen, MT; Magnuson, B; Ljungman, M; Park, D; Zhang, C; Campbell, ZT; Goldstrohm, AC; Freddolino, PL

Freddolino, PL (corresponding author), Univ Michigan, Dept Biol Chem, Ann Arbor, MI 48109 USA.; Freddolino, PL (corresponding author), Univ Michigan, Dept Computat Med & Bioinformat, Ann Arbor, MI 48109 USA.; Goldstrohm, AC (corresponding author), Univ Minnesota, Dept Biochem Mol Biol & Biophys, Minneapolis, MN 55455 USA.

RNA, 2020; 26 (11): 1680

Abstract

The human PUF-family proteins, PUM1 and PUM2, posttranscriptionally regulate gene expression by binding to a PUM recognition element (PRE) in the 3'-U......

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