The effects of PEGylation on LNP based mRNA delivery to the eye

Ryals, RC; Patel, S; Acosta, C; McKinney, M; Pennesi, ME; Sahay, G

Sahay, G (corresponding author), Oregon Hlth & Sci Univ, Dept Ophthalmol, Casey Eye Inst, Portland, OR 97201 USA.; Sahay, G (corresponding author), Oregon State Univ, Coll Pharm, Dept Pharmaceut Sci, Portland, OR 97204 USA.

PLOS ONE, 2020; 15 (10):

Abstract

Gene therapy is now an effective approach to treat many forms of retinal degeneration. Delivery agents that are cell-specific, allow for multiple dosi......

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