Association of NUDT15 c.415C > T and FPGS 2572C > T Variants with the Risk of Early Hematologic Toxicity During 6-MP and Low-Dose Methotrexate-Based Maintenance Therapy in Indian Patients with Acute Lymphoblastic Leukemia

Kodidela, S; Dorababu, P; Thakkar, DN; Dubashi, B; Sundaram, R; Muralidharan, N; Nidanapu, RP; Aribandi, A; Pradhan, SC; Uppugunduri, CRS

Kodidela, S (corresponding author), Univ Tennessee, Hlth Sci Ctr, Coll Pharm, Memphis, TN 38163 USA.; Uppugunduri, CRS (corresponding author), Univ Geneva, Oncohematol Unit, Res Platform Pediat Oncohematol, Dept Paediat Gynaecol & Obstet,Univ Hosp Geneva, CH-1205 Geneva, Switzerland.

GENES, 2020; 11 (6):

Abstract

Genetic variants influencing the pharmacokinetics and/or pharmacodynamics of the chemotherapeutic drugs used in Acute Lymphoblastic Leukemia (ALL) the......

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