The AML-associated K313 mutation enhances C/EBP alpha activity by leading to C/EBP alpha overexpression

Gentle, IE; Moelter, I; Badr, MT; Dohner, K; Lubbert, M; Hacker, G

Gentle, IE (corresponding author), Univ Freiburg, Fac Med, Med Ctr, Inst Med Microbiol & Hyg, D-79104 Freiburg, Germany.

CELL DEATH & DISEASE, 2021; 12 (7):

Abstract

Mutations in the transcription factor C/EBP alpha are found in similar to 10% of all acute myeloid leukaemia (AML) cases but the contribution of these......

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