Antitumor effect of plant-produced anti-CTLA-4 monoclonal antibody in a murine model of colon cancer

Bulaon, CJI; Khorattanakulchai, N; Rattanapisit, K; Sun, HY; Pisuttinusart, N; Strasser, R; Tanaka, S; Soon-Shiong, P; Phoolcharoen, W

Phoolcharoen, W (通讯作者)，Chulalongkorn Univ, Ctr Excellence Plant Produced Pharmaceut, Bangkok, Thailand.;Phoolcharoen, W (通讯作者)，Chulalongkorn Univ, Fac Pharmaceut Sci, Dept Pharmacognosy & Pharmaceut Bot, Bangkok, Thailand.

FRONTIERS IN PLANT SCIENCE, 2023; 14 ():

Abstract

Cytotoxic T lymphocyte-associated protein 4 (CTLA-4) is an immune checkpoint regulator exclusively expressed on T cells that obstructs the cell's effe......

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