SCI: A Bayesian adaptive phase I/II dose-finding design accounting for semi-competing risks outcomes for immunotherapy trials

Zhang, YF; Guo, BB; Cao, S; Zhang, C; Zang, Y

Zang, Y (通讯作者),Indiana Univ, Dept Biostat & Hlth Data Sci, 410 W 10th St, Indianapolis, IN 46075 USA.

PHARMACEUTICAL STATISTICS, 2022; 21 (5): 960

Abstract

An immunotherapy trial often uses the phase I/II design to identify the optimal biological dose, which monitors the efficacy and toxicity outcomes sim......

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