GRAMD1/ASTER-mediated cholesterol transport promotes Smoothened cholesterylation at the endoplasmic reticulum

Qiu, ZP; Lin, ZC; Hu, A; Liu, YB; Zeng, WE; Zhao, XL; Shi, XJ; Luo, J; Song, BL

Song, BL (通讯作者)，Wuhan Univ, Coll Life Sci, Taikang Ctr Life & Med Sci, Hubei Key Lab Cell Homeostasis,Taikang Med Sch, Wuhan, Peoples R China.

EMBO JOURNAL, 2023; 42 (3):

Abstract

Hedgehog (Hh) signaling pathway plays a pivotal role in embryonic development. Hh binding to Patched1 (PTCH1) derepresses Smoothened (SMO), thereby ac......

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