Development of RNA G-quadruplex (rG4)-targeting l-RNA aptamers by rG4-SELEX

Umar, MI; Chan, CY; Kwok, CK

Kwok, CK (通讯作者)，City Univ Hong Kong, Dept Chem, Kowloon Tong, Hong Kong, Peoples R China.;Kwok, CK (通讯作者)，City Univ Hong Kong, State Key Lab Marine Pollut, Kowloon Tong, Hong Kong, Peoples R China.;Kwok, CK (通讯作者)，City Univ Hong Kong, Shenzhen Res Inst, Shenzhen, Peoples R China.

NATURE PROTOCOLS, 2022; 17 (6): 1385

Abstract

RNA G-quadruplex (rG4)-SELEX is a method that generates L-RNA aptamers to target an rG4 structure of interest, which can be applied to inhibit G-quadr......

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