Reprogramming of IL-12 secretion in the PDCD1 locus improves the anti-tumor activity of NY-ESO-1 TCR-T cells

Kim, S; Park, CI; Lee, SH; Choi, HR; Kim, CH

Kim, CH (通讯作者),Korea Adv Inst Sci & Technol, Dept Biol Sci, Daejeon, South Korea.

FRONTIERS IN IMMUNOLOGY, 2023; 14 ():

Abstract

IntroductionAlthough the engineering of T cells to co-express immunostimulatory cytokines has been shown to enhance the therapeutic efficacy of adopti......

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