EZH2 restricts Tcf7 DNA methylation and promotes T-FH differentiation during acute viral infection

Luo, Y; Li, D; Xie, LYZ; Lei, S; Chen, XY; Wang, C; Yao, D; Li, L; Fang, JY; Chen, C; Yuan, SJ; Li, F; Xie, XR; Zhang, Y; Li, ZR; Hu, L; Tang, JF; Ye, LL; Wei, ZP; He, R

He, R (通讯作者)，Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Basic Med, Dept Immunol, Wuhan, Peoples R China.;Wei, ZP (通讯作者)，Third Mil Med Univ, Inst Immunol, Chongqing, Peoples R China.;Wei, ZP (通讯作者)，Southern Med Univ, Dermatol Hosp, Guangzhou, Peoples R China.

FRONTIERS IN IMMUNOLOGY, 2022; 13 ():

Abstract

Follicular helper T (T-FH) cells provide specialized help for B cells to ensure optimal humoral immunity. The histone methyltransferase EZH2, as a chr......

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