Efficacy and safety of the investigational complement C5 inhibitor zilucoplan in patients hospitalized with COVID-19: an open-label randomized controlled trial

De Leeuw, E; Van Damme, KFA; Declercq, J; Bosteels, C; Maes, B; Tavernier, SJ; Detalle, L; Smart, T; Glatt, S; Debeuf, N; Deckers, J; Lameire, S; Vandecasteele, SJ; De Neve, N; Demedts, IK; Govaerts, E; Knoop, C; Vanhove, K; Moutschen, M; Terryn, W; Depuydt, P; Van Braeckel, E; Haerynck, F; Hendrickx, TCJ; Parrein, V; Lalla, M; Brittain, C; Lambrecht, BN

Lambrecht, BN (通讯作者),Univ Ghent, VIB UGent Ctr Inflammat Res, Lab Mucosal Immunol, Technol Pk Zwijnaarde 71, B-9052 Ghent, Belgium.;Lambrecht, BN (通讯作者),Univ Ghent, Fac Med & Hlth Sci, Dept Internal Med & Pediat, Ghent, Belgium.;Lambrecht, BN (通讯作者),Ghent Univ Hosp, Dept Resp Med, Ghent, Belgium.

RESPIRATORY RESEARCH, 2022; 23 (1):

Abstract

Background The efficacy and safety of complement inhibition in COVID-19 patients is unclear. Methods A multicenter randomized controlled, open-label t......

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