Development of a Fast and Sensitive UPLC-MS/MS Analytical Methodology for Fenebrutinib Estimation in Human Liver Microsomes: In Vitro and In Silico Metabolic Stability Evaluation

Attwa, MW; Alsibaee, AM; Aljohar, HI; Abdelhameed, AS; Kadi, AA

Attwa, MW (通讯作者)，King Saud Univ, Coll Pharm, Dept Pharmaceut Chem, Riyadh 11451, Saudi Arabia.

SEPARATIONS, 2023; 10 (5):

Abstract

Fenebrutinib (GDC-0853; FNB) is an oral small molecule that was developed by Roche Pharmaceuticals to slow multiple sclerosis progression. FNB is a re......

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