Disordered Regions Flanking the Binding Interface Modulate Affinity between CBP and NCOA

Karlsson, E; Schnatwinkel, J; Paissoni, C; Andersson, E; Herrmann, C; Camilloni, C; Jemth, P

Jemth, P (通讯作者),Uppsala Univ, Dept Med Biochem & Microbiol, BMC Box 582, SE-75123 Uppsala, Sweden.;Camilloni, C (通讯作者),Univ Milan, Dipartimento Biosci, I-20133 Milan, Italy.

JOURNAL OF MOLECULAR BIOLOGY, 2022; 434 (13):

Abstract

Recognition motifs that mediate protein-protein interactions are usually embedded within longer intrinsically disordered regions. While binding interf......

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