Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation

Janas, JA; Zhang, LC; Luu, JH; Demeter, J; Meng, LJ; Marro, SG; Mall, M; Mooney, NA; Schaukowitch, K; Ng, YH; Yang, N; Huang, YH; Neumayer, G; Gozani, O; Elias, JE; Jackson, PK; Wernig, M

Wernig, M (通讯作者)，Stanford Univ, Dept Pathol, Sch Med, Stanford, CA 94305 USA.;Wernig, M (通讯作者)，Stanford Univ, Inst Stem Cell Biol & Regenerat Med, Sch Med, Stanford, CA 94305 USA.;Wernig, M (通讯作者)，Stanford Univ, Dept Chem & Syst Biol, Sch Med, Stanford, CA 94305 USA.

MOLECULAR CELL, 2022; 82 (24): 4627

Abstract

Cell lineage specification is accomplished by a concerted action of chromatin remodeling and tissue -specific transcription factors. However, the mech......

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