Specific N-terminal amino acids potentiate the periplasmic expression of single-chain variable fragments in Escherichia coli

Hanyu, Y; Kato, M

Hanyu, Y (通讯作者),Hlth & Med Res Inst, Natl Inst Adv Ind Sci & Technol AIST, Biomat Res Grp, 1-1-1 Higashi, Tsukuba 3058566, Japan.

BIOTECHNIQUES, 2023; 74 (2): 107

Abstract

Single-chain variable fragments (ScFvs) are important in therapy, diagnosis and research because of their elevated antigen affinity and low immunogeni......

Full Text Link