Radiosynthesis and preliminary evaluation of C-11-labeled 4-cyclopropyl-7-(3-methoxyphenoxy)-3,4-dihydro-2H-benzo[e] [1,2,4] thiadiazine 1,1-dioxide for PET imaging AMPA receptors

Chen, JH; Gan, JF; Sun, JY; Chen, Z; Fu, HL; Rong, J; Deng, XY; Shang, JJ; Gong, J; Shao, T; Collier, L; Wang, L; Xu, H; Liang, SH

Xu, H (corresponding author), Jinan Univ, Affiliated Hosp 1, Dept Nucl Med, 613 West Huangpu Rd, Guangzhou 510630, Peoples R China.; Xu, H (corresponding author), Jinan Univ, Affiliated Hosp 1, PET CT MRI Ctr, 613 West Huangpu Rd, Guangzhou 510630, Peoples R China.; Liang, SH (corresponding author), Massachusetts Gen Hosp, Div Nucl Med & Mol Imaging, Boston, MA 02114 USA.; Liang, SH (corresponding author), Harvard Med Sch, Dept Radiol, Boston, MA 02114 USA.

TETRAHEDRON LETTERS, 2020; 61 (12):

Abstract

The alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) belong to the family of ionotropic transmembrane receptors for glutam......

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