From Antisense RNA to RNA Modification: Therapeutic Potential of RNA-Based Technologies

Adachi, H; Hengesbach, M; Yu, YT; Morais, P

Yu, YT (corresponding author), Univ Rochester, Med Ctr, Dept Biochem & Biophys, Ctr RNA Biol, 601 Elmwood Ave, Rochester, NY 14642 USA.; Morais, P (corresponding author), ProQR Therapeut, Zernikedreef 9, NL-2333 CK Leiden, Netherlands.

BIOMEDICINES, 2021; 9 (5):

Abstract

Therapeutic oligonucleotides interact with a target RNA via Watson-Crick complementarity, affecting RNA-processing reactions such as mRNA degradation,......

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