Functional Variation of IL-1R-Associated Kinases in the Conserved MyD88-TRAF6 Pathway during Evolution

Yan, XY; Chen, SH; Huang, HQ; Peng, T; Lan, MJ; Yang, X; Dong, ML; Chen, SW; Xu, AL; Huang, SF

Xu, AL; Huang, SF (corresponding author), Sun Yat Sen Univ, Sch Life Sci, State Key Lab Biocontrol, Guangdong Key Lab Pharmaceut Funct Genes, 135 Xingang West St, Guangzhou 510275, Guangdong, Peoples R China.

JOURNAL OF IMMUNOLOGY, 2020; 204 (4): 832

Abstract

IL-1R-associated kinases (IRAK) are important regulators in the TLR/IL-1R pathways, but their function appears inconsistent between Drosophila, bony f......

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