REFINE-Lung implements a novel multi-arm randomisedtrial design to address possible immunotherapy overtreatment

Ghorani, E; Quartagno, M; Blackhall, F; Gilbert, DC; O'Brien, M; Ottensmeier, C; Pizzo, E; Spicer, J; Williams, A; Badman, P; Parmar, MKB; Seckl, MJ

Seckl, MJ (通讯作者),Imperial Coll London, Charing Cross Gestat Trophoblast Dis Ctr, Dept Med Oncol, Charing Cross Hosp Campus, London W6 8RF, England.;Parmar, MKB (通讯作者),UCL, Inst Clin Trials & Methodol, London WC1V 6LJ, England.

LANCET ONCOLOGY, 2023; 24 (5): E219

Abstract

Increasing evidence suggests that some immunotherapy dosing regimens for patients with advanced cancer could result in overtreatment. Given the high c......

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