Synergy and allostery in ligand binding by HIV-1 Nef

Aldehaiman, A; Momin, AA; Restouin, A; Wang, LY; Shi, XL; Aljedani, S; Opi, S; Lugari, A; Hameed, UFS; Ponchon, L; Morelli, X; Huang, MD; Dumas, C; Collette, Y; Arold, ST

Arold, ST (corresponding author), King Abdullah Univ Sci & Technol KAUST, Computat Biosci Res Ctr CBRC, Biol & Environm Sci & Engn BESE, Thuwal 239556900, Saudi Arabia.; Arold, ST (corresponding author), Univ Montpellier, Ctr Biochim Struct, INSERM, CNRS, F-34090 Montpellier, France.

BIOCHEMICAL JOURNAL, 2021; 478 (8): 1525

Abstract

The Nef protein of human and simian immunodeficiency viruses boosts viral pathogenicity through its interactions with host cell proteins. By combining......

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