The ocular pharmacokinetics and biodistribution of phospho-sulindac (OXT-328) formulated in nanoparticles: Enhanced and targeted tissue drug delivery

Wen, ZY; Muratomi, N; Huang, W; Huang, LQ; Ren, JF; Yang, J; Persaud, Y; Loloi, J; Mallangada, N; Kung, P; Honkanen, R; Rigas, B

Rigas, B (reprint author), SUNY Stony Brook, Dept Prevent Med, Hlth Sci Ctr T17 080, Stony Brook, NY 11794 USA.

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2019; 557 (): 273

Abstract

We studied the pharmacokinetics, biodistribution and metabolism of phospho-sulindac (PS), a novel agent efficacious in the treatment of dry eye, formu......

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