Nonionic, Cleavable Surfactant for Top-Down Proteomics

Brown, KA; Gugger, MK; Yu, Z; Moreno, D; Jin, S; Ge, Y

Brown, KA; Ge, Y (通讯作者),Univ Wisconsin Madison, Dept Chem, Madison, WI 53706 USA.;Ge, Y (通讯作者),Univ Wisconsin Madison, Dept Cell & Regenerat Biol, Madison, WI 53705 USA.;Ge, Y (通讯作者),Univ Wisconsin Madison, Human Prote Program, Madison, WI 53705 USA.;Brown, KA (通讯作者),Univ Wisconsin Madison, Dept Surg, Madison, WI 53705 USA.

ANALYTICAL CHEMISTRY, 2023; 95 (3): 1801

Abstract

Nonionic surfactants are often used as general reagents for cell lysis enabling protein extraction, stabilization, and purification under nondenaturin......

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