Optimization of 8-oxoadenines with toll-like-receptor 7 and 8 activity

Bazin, HG; Bess, LS; Livesay, MT; Li, YF; Cybulski, V; Miller, SM; Johnson, DA; Evans, JT

Bazin, HG (corresponding author), Univ Montana, Ctr Translat Med, Missoula, MT 59812 USA.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020; 30 (6):

Abstract

Toll-like receptors 7 and 8 (TLR7/8) agonists are potent immunostimulants that are attracting considerable interest as vaccine adjuvants. We recently ......

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