Mobile element warfare via CRISPR and anti-CRISPR in Pseudomonas aeruginosa

Leon, LM; Park, AE; Borges, AL; Zhang, JY; Bondy-Denomy, J

Bondy-Denomy, J (corresponding author), Univ Calif San Francisco, Dept Microbiol & Immunol, San Francisco, CA 94158 USA.; Bondy-Denomy, J (corresponding author), Univ Calif San Francisco, Quantitat Biosci Inst, San Francisco, CA 94158 USA.; Bondy-Denomy, J (corresponding author), Innovat Genom Inst, Berkeley, CA 94720 USA.

NUCLEIC ACIDS RESEARCH, 2021; 49 (4): 2114

Abstract

Bacteria deploy multiple defenses to prevent mobile genetic element (MGEs) invasion. CRISPR-Cas immune systems use RNA-guided nucleases to target MGEs......

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