COVIDENZA - A prospective, multicenter, randomized PHASE II clinical trial of enzalutamide treatment to decrease the morbidity in patients with Corona virus disease 2019 (COVID-19): a structured summary of a study protocol for a randomised controlled trial

Welen, K; Overby, AK; Ahlm, C; Freyhult, E; Robinsson, D; Henningsson, AJ; Stranne, J; Bremell, D; Angelin, M; Lindquist, E; Buckland, R; Carlsson, CT; Pauksens, K; Bill-Axelsson, A; Akre, O; Ryden, C; Wagenius, M; Bjartell, A; Nilsson, AC; Styrke, J; Repo, J; Balkhed, AO; Niward, K; Gisslen, M; Josefsson, A

Welen, K; Josefsson, A (corresponding author), Univ Gothenburg, Sahlgrenska Ctr Canc Res, Inst Clin Sci, Dept Urol,Sahlgrenska Acad, S-40530 Gothenburg, Sweden.; Josefsson, A (corresponding author), Umea Univ, Dept Surg & Perioperat Sci Urol & Androl, S-90187 Umea, Sweden.; Josefsson, A (corresponding author), Umea Univ, Wallenberg Ctr Mol Med, Umea, Sweden.

TRIALS, 2021; 22 (1):

Abstract

Objectives: The main goal of the COVIDENZA trial is to evaluate if inhibition of testosterone signalling by enzalutamide can improve the outcome of pa......

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