DNMT3A Mutation-Induced CDK1 Overexpression Promotes Leukemogenesis by Modulating the Interaction between EZH2 and DNMT3A

Yang, Y; Dai, YJ; Yang, XJ; Wu, SF; Wang, YY

Wang, YY (corresponding author), Shanghai Jiao Tong Univ, Rui Jin Hosp, Natl Res Ctr Translat Med Shanghai,Sch Med, Shanghai Inst Hematol,State Key Lab Med Genom, Shanghai 200025, Peoples R China.

BIOMOLECULES, 2021; 11 (6):

Abstract

DNMT3A mutations are frequently identified in acute myeloid leukemia (AML) and indicate poor prognosis. Previously, we found that the hotspot mutation......

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