Rapid Microfluidic Dilution for Single-Molecule Spectroscopy of Low-Affinity Biomolecular Complexes

Zijlstra, N; Dingfelder, F; Wunderlich, B; Zosel, F; Benke, S; Nettels, D; Schuler, B

Schuler, B (reprint author), Univ Zurich, Dept Biochem, Winterthurerstr 190, CH-8057 Zurich, Switzerland.; Schuler, B (reprint author), Univ Zurich, Dept Phys, Winterthurerstr 190, CH-8057 Zurich, Switzerland.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2017; 56 (25): 7126

Abstract

To enable the investigation of low-affinity biomolecular complexes with confocal single-molecule spectroscopy, we have developed a microfluidic device......

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