Integrin beta 1 overexpression protects nucleus pulposus cells from apoptosis and attenuates intervertebral disc degeneration

Du, L; Zhou, TJ; Ma, ZJ; Tian, HJ; Qin, A; Zhang, K; Zhao, CQ; Zhao, J

Zhao, CQ; Zhao, J (reprint author), Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 9, Sch Med, Dept Orthoped,Shanghai Key Lab Orthoped Implants, 639 Zhizaoju Rd, Shanghai 200011, Peoples R China.

INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2017; 10 (5): 5285

Abstract

Intervertebral disc (IVD) degeneration is a chronic pathologic process characterized by excessive apoptosis of intervertebral disc cells. The purpose ......

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