Cotargeting of MEK and PDGFR/STAT3 Pathways to Treat Pancreatic Ductal Adenocarcinoma

Sahu, N; Chan, E; Chu, F; Pham, T; Koeppen, H; Forrest, W; Merchant, M; Settleman, J

Settleman, J (reprint author), Calico Life Sci, 1170 Vet Blvd, San Francisco, CA 94080 USA.

MOLECULAR CANCER THERAPEUTICS, 2017; 16 (9): 1729

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is among the most lethal human diseases and remains largely refractory to available drug treatments. Insuffici......

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