Low-dose decitabine modulates myeloid-derived suppressor cell fitness via LKB1 in immune thrombocytopenia

Ni, XF; Wang, LJ; Wang, HY; Yu, TS; Xie, J; Li, GS; Liu, YF; Zhou, H; Xu, M; Hou, M; Peng, J; Hou, Y

Hou, Y (通讯作者),Shandong Univ, Qilu Hosp, Cheeloo Coll Med, Dept Hematol, 107 Wenhuaxi Rd, Jinan 250012, Peoples R China.

BLOOD, 2022; 140 (26): 2818

Abstract

Myeloid-derived suppressor cells (MDSCs) are heterogeneous immature cells and natural inhibitors of adaptive immunity. Metabolic fitness of MDSCs is f......

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