EGFR stimulation enables IL-6 trans-signalling via iRhom2-dependent ADAM17 activation in mammary epithelial cells

Schumacher, N; Thomsen, I; Brundert, F; Hejret, V; Düsterhöft, S; Tichy, B; Schmidt-Arras, D; Voss, M; Rose-John, S

Schumacher, N (通讯作者)，Christian Albrechts Univ Kiel, Inst Biochem, Rudolf Hober Str 1, D-24118 Kiel, Germany.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2023; 1870 (7):

Abstract

The cytokine interleukin-6 (IL-6) has considerable pro-inflammatory properties and is a driver of many physiological and pathophysiological processes.......

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