Intranasal 15d-PGJ2 ameliorates brain glucose hypometabolism via PPAR gamma-dependent activation of PGC-1 alpha/GLUT4 signalling in APP/PS1 transgenic mice

Li, ZY; Zhang, Y; Zheng, YY; Liu, WL; Zhang, XJ; Li, WP; Zhang, D; Cai, Q; Wang, SC; Meng, XB; Huang, GD

Meng, XB; Huang, GD (corresponding author), Shenzhen Univ, Affiliated Hosp 1, Shenzhen Peoples Hosp 2, Inst Translat Med,Dept Neurosurg,Shenzhen Key Lab, 3002 Sungang Westrd, Shenzhen 518035, Peoples R China.

NEUROPHARMACOLOGY, 2021; 196 ():

Abstract

Targeting the common molecular mechanism of type 2 diabetes mellitus and Alzheimer's disease (AD), including dysregulation of glucose metabolism, insu......

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