Peli1 contributes to myocardial ischemia/reperfusion injury by impairing autophagy flux via its E3 ligase mediated ubiquitination of P62

Yang, J; Tong, TT; Zhu, CH; Zhou, M; Jiang, YQ; Chen, H; Que, LL; Liu, L; Zhu, GQ; Ha, T; Chen, Q; Li, CF; Xu, Y; Li, JT; Li, YH

Li, JT; Li, YH (通讯作者)，Nanjing Med Univ, Collaborat Innovat Ctr Cardiovasc Dis Translat Med, Key Lab Targeted Intervent Cardiovasc Dis, Nanjing 211166, Jiangsu, Peoples R China.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2022; 173 (): 30

Abstract

Autophagy flux is impaired during myocardial ischemia/reperfusion (M-I/R) via the accumulation of autopha-gosome and insufficient clearance, which exa......

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