Hyperhomocysteinemia induces vascular calcification by activating the transcription factor RUNX2 via Kr?ppel-like factor 4 up-regulation in mice

Zhu, LL; Zhang, N; Yan, R; Yang, WJ; Cong, GZ; Yan, N; Ma, WR; Hou, JJ; Yang, LB; Jia, SB

Jia, SB (reprint author), Ningxia Med Univ, Gen Hosp, Inst Cardiovasc Dis, Yinchuan 750001, Ningxia, Peoples R China.

JOURNAL OF BIOLOGICAL CHEMISTRY, 2019; 294 (51): 19465

Abstract

One of the main characteristics of atherosclerosis is vascular calcification, which is linked to adverse cardiovascular events. Increased homocysteine......

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