Atypical activation of the G protein G(q) by the oncogenic mutation Q209P

Maziarz, M; Leyme, A; Marivin, A; Luebbers, A; Patel, PP; Chen, Z; Sprang, SR; Garcia-Marcos, M

Garcia-Marcos, M (reprint author), Boston Univ, Sch Med, Dept Biochem, 72 E Concord St,Silvio Conte Bldg K, Boston, MA 02118 USA.

JOURNAL OF BIOLOGICAL CHEMISTRY, 2018; 293 (51): 19586

Abstract

The causative role of G protein-coupled receptor (GPCR) pathway mutations in uveal melanoma (UM) has been well-established. Nearly all UMs bear an act......

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