Protease XIV abolishes NHE inhibition by empagliflozin in cardiac cells

Chen, S; Schumacher, CA; Van Amersfoorth, SCM; Fiolet, JWT; Baartscheer, A; Veldkamp, MW; Coronel, R; Zuurbier, CJ

Zuurbier, CJ (通讯作者)，Amsterdam UMC, Dept Anaesthesiol, Lab Expt Intens Care & Anaesthesiol LEICA, Locat AMC, Amsterdam, Netherlands.;Zuurbier, CJ (通讯作者)，Amsterdam Cardiovasc Sci, Atherosclerosis & Ischem Syndromes, Amsterdam, Netherlands.

FRONTIERS IN PHYSIOLOGY, 2023; 14 ():

Abstract

Background: SGLT2i directly inhibit the cardiac sodium-hydrogen exchanger-1 (NHE1) in isolated ventricular cardiomyocytes (CMs). However, other studie......

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