CYP2J2-produced epoxyeicosatrienoic acids attenuate ischemia/reperfusion-induced acute kidney injury by activating the SIRT1-FoxO3a pathway

Zhu, Y; Ding, A; Yang, DL; Cui, TX; Yang, H; Zhang, H; Wang, C

Zhu, Y; Wang, C (corresponding author), Sun Yat Sen Univ, Dept Nephrol, Affiliated Hosp 5, Mei Hua Dong Rd 52, Zhuhai 519000, Guangdong, Peoples R China.

LIFE SCIENCES, 2020; 246 ():

Abstract

Cytochrome P450 (CYP) epoxygenases can metabolize arachidonic acids to epoxyeicosatrienoic acids (EETs), which play a protective role in the renal sys......

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