Bioinformatics driven discovery of small molecule compounds that modulate the FOXM1 and PPARA pathway activities in breast cancer

Huang, SJ; Hu, PZ; Lakowski, TM

Lakowski, TM (通讯作者),Univ Manitoba, Coll Pharm, Apotex Ctr, 750 McDermot Ave, Winnipeg, MB R3E 0T5, Canada.;Hu, PZ (通讯作者),Western Univ, Schulich Sch Med & Dent, Dept Biochem, London, ON N6A 5C1, Canada.;Lakowski, TM (通讯作者),CancerCare Manitoba, Res Inst Oncol & Hematol, 675 McDermot Aveune, Winnipeg, MB R3E 0T5, Canada.

PHARMACOGENOMICS JOURNAL, 2023; 23 (4): 61

Abstract

Our previous studies demonstrated that the FOXM1 pathway is upregulated and the PPARA pathway downregulated in breast cancer (BC), and especially in t......

Full Text Link