Structure of CRL7(FBXW)(8) reveals coupling with CUL1-RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation

Hopf, LVM; Baek, K; Klgel, M; Von Gronau, S; Xiong, Y; Schulman, BA

Schulman, BA (通讯作者)，Max Planck Inst Biochem, Dept Mol Machines & Signaling, Martinsried, Germany.

NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2022; 29 (9): 854

Abstract

Most cullin-RING ubiquitin ligases (CRLs) form homologous assemblies between a neddylated cullin-RING catalytic module and a variable substrate-bindin......

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