Central repeat fragment of reelin leads to active reelin intracellular signaling and rescues cognitive deficits in a mouse model of reelin deficiency

Li, QY; Morrill, NK; Moerman-Herzog, AM; Barger, SW; Joly-Amado, A; Peters, M; Soueidan, H; Diemler, C; Prabhudeva, S; Weeber, EJ; Nash, KR

Nash, KR (通讯作者),Univ S Florida, Morsani Coll Med, Dept Mol Pharmacol & Physiol, 12901 Bruce B Downs Blvd, Tampa, FL 33612 USA.

CELLULAR SIGNALLING, 2023; 109 ():

Abstract

Reelin and its receptor, ApoER2, play important roles in prenatal brain development and postnatally in synaptic plasticity, learning, and memory. Prev......

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