Inhibition of Bcl-xL prevents pro-death actions of Delta N-Bcl-xL at the mitochondrial inner membrane during glutamate excitotoxicity

Park, HA; Licznerski, P; Mnatsakanyan, N; Niu, YL; Sacchetti, S; Wu, J; Polster, BM; Alavian, KN; Jonas, EA

Jonas, EA (reprint author), Yale Univ, Sch Med, Sect Endocrinol, Dept Internal Med, POB 20802, New Haven, CT 06511 USA.

CELL DEATH AND DIFFERENTIATION, 2017; 24 (11): 1963

Abstract

ABT-737 is a pharmacological inhibitor of the anti-apoptotic activity of B-cell lymphoma-extra large (Bcl-xL) protein; it promotes apoptosis of cancer......

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