Camptothecin and Topotecan, Inhibitors of Transcription Factor Fli-1 and Topoisomerase, Markedly Ameliorate Lupus Nephritis in (NZB x NZW)F1 Mice and Reduce the Production of Inflammatory Mediators in Human Renal Cells

Wang, X; Oates, JC; Helke, KL; Gilkeson, GS; Zhang, XK

Zhang, XK (corresponding author), Med Univ South Carolina, Div Rheumatol & Immunol, 96 Jonathan Lucas St,Suite 912,MSC 637, Charleston, SC 29425 USA.

ARTHRITIS & RHEUMATOLOGY, 2021; 73 (8): 1478

Abstract

Objective To examine the therapeutic effects of camptothecin (CPT) and topotecan (TPT), inhibitors of transcription factor Fli-1 and topoisomerase, on......

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