Inhibition of Fatty Acid Synthesis Aggravates Brain Injury, Reduces Blood-Brain Barrier Integrity and Impairs Neurological Recovery in a Murine Stroke Model

Janssen, L; Ai, XY; Zheng, X; Wei, W; Caglayan, AB; Kilic, E; Wang, YC; Hermann, DM; Venkataramani, V; Bahr, M; Doeppner, TR

Doeppner, TR (corresponding author), Univ Med Ctr Gottingen, Dept Neurol, Gottingen, Germany.; Doeppner, TR (corresponding author), Istanbul Medipol Univ, Regenerat & Restorat Med Res Ctr, Istanbul, Turkey.

FRONTIERS IN CELLULAR NEUROSCIENCE, 2021; 15 ():

Abstract

Inhibition of fatty acid synthesis (FAS) stimulates tumor cell death and reduces angiogenesis. When SH-SY5Y cells or primary neurons are exposed to hy......

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