Molecular, Solid-State and Surface Structures of the Conformational Polymorphic Forms of Ritonavir in Relation to their Physicochemical Properties

Wang, C; Rosbottom, I; Turner, TD; Laing, S; Maloney, AGP; Sheikh, AY; Docherty, R; Yin, QX; Roberts, KJ

Turner, TD (corresponding author), Univ Leeds, Ctr Digital Design Drug Prod, Sch Chem & Proc Engn, Woodhouse Lane, Leeds LS2 9JT, W Yorkshire, England.

PHARMACEUTICAL RESEARCH, 2021; 38 (6): 971

Abstract

Purpose Application of multi-scale modelling workflows to characterise polymorphism in ritonavir with regard to its stability, bioavailability and pro......

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