PI3K/AKT pathway mediates the antidepressant- and anxiolytic-like roles of hydrogen sulfide in streptozotocin-induced diabetic rats via promoting hippocampal neurogenesis

Jiang, W; Tang, YY; Zhu, WW; Li, C; Zhang, P; Li, RQ; Chen, YJ; Zou, W; Tang, XQ

Zhang, P (corresponding author), Univ South China, Affiliated Nanhua Hosp, Dept Neurol, 336 5 Dongfeng Rd, Hengyang 421001, Hunan, Peoples R China.; Tang, XQ (corresponding author), Univ South China, Affiliated Hosp 1, Inst Neurol, 69 Chuanshan Rd, Hengyang 421001, Hunan, Peoples R China.

NEUROTOXICOLOGY, 2021; 85 (): 201

Abstract

We have previously demonstrated that hydrogen sulfide (H2S), the third endogenous gasotransmitter, ameliorates the depression- and anxiety-like behavi......

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