Antimalarial N-1,N-3-Dialkyldioxonaphthoimidazoliums: Synthesis, Biological Activity, and Structure-activity Relationships

Ahenkorah, S; Coertzen, D; Tong, JX; Fridianto, K; Wittlin, S; Birkholtz, LM; Tan, KSW; Lam, Y; Go, ML; Haynes, RK

Go, ML (corresponding author), Natl Univ Singapore, Dept Pharm, Singapore 117543, Singapore.; Haynes, RK (corresponding author), North West Univ, Ctr Excellence Pharmaceut Sci, ZA-2531 Potchefstroom, South Africa.

ACS MEDICINAL CHEMISTRY LETTERS, 2020; 11 (1): 49

Abstract

Here we report the nanomolar potencies of N-1,N-3-dialkyldioxonaphthoimidazoliums against asexual forms of sensitive and resistant Plasmodium falcipar......

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