Synthesis of alpha-Deuterioalcohols by Single-Electron Umpolung Reductive Deuteration of Carbonyls Using D (2) O as Deuterium Source

Li, HZ; Hou, YX; Lai, ZM; Ning, L; Li, AL; Li, YX; An, J

Li, YX; An, J (corresponding author), China Agr Univ, Dept Nutr & Hlth, Beijing 100193, Peoples R China.

SYNLETT, 2021; 32 (12): 1241

Abstract

Deuterium incorporation can effectively stabilize the chiral centers of drug and agrochemical candidates that hampered by rapid in vivo racemization. ......

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