Engineering SARS-CoV-2 using a reverse genetic system

Xie, XP; Lokugamage, KG; Zhang, XW; Vu, MN; Muruato, AE; Menachery, VD; Shi, PY

Shi, PY (corresponding author), Univ Texas Med Branch, Dept Biochem & Mol Biol, Galveston, TX 77555 USA.; Menachery, VD (corresponding author), Univ Texas Med Branch, Dept Microbiol & Immunol, Galveston, TX 77555 USA.; Menachery, VD; Shi, PY (corresponding author), Univ Texas Med Branch, Inst Human Infect & Immun, Galveston, TX 77555 USA.; Menachery, VD (corresponding author), Univ Texas Med Branch, Ctr Biodefense & Emerging Infect Dis, Galveston, TX 77555 USA.; Shi, PY (corresponding author), U

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Abstract

Reverse genetic systems are a critical tool for studying viruses and identifying countermeasures. In response to the ongoing COVID-19 pandemic, we rec......

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