Human tau pathology transmits glial tau aggregates in the absence of neuronal tau

Narasimhan, S; Changolkar, L; Riddle, DM; Kats, A; Stieber, A; Weitzman, SA; Zhang, B; Li, ZY; Roberson, ED; Trojanowski, JQ; Lee, VMY

Lee, VMY (corresponding author), Univ Penn, Sch Med, Dept Pathol & Lab Med, Inst Aging, Philadelphia, PA 19104 USA.; Lee, VMY (corresponding author), Univ Penn, Sch Med, Ctr Neurodegenerat Dis Res, Philadelphia, PA 19104 USA.

JOURNAL OF EXPERIMENTAL MEDICINE, 2020; 217 (2):

Abstract

Tauopathies are characterized by abnormal accumulation of tau protein in neurons and glia. In Alzheimer's disease (AD), tau aggregates in neurons, whi......

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