Murine Retinal Citrullination Declines With Age and is Mainly Dependent on Peptidyl Arginine Deiminase 4 (PAD4)

Hollingsworth, TJ; Radic, MZ; Beranova-Giorgianni, S; Giorgianni, F; Wang, YM; Iannaccone, A

Iannaccone, A (reprint author), Duke Univ, Sch Med, Duke Eye Ctr, Dept Ophthalmol, 2351 Erwin Rd,DUMC Box 3802, Durham, NC 27710 USA.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2018; 59 (10): 3808

Abstract

PURPOSE. Citrullination is a post-translational modification (PTM) that serves many normal physiological functions. Studies have shown that this PTM-a......

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